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Despite treatment advancement in metastatic castration-resistant prostate cancer (mCRPC)NEW YORK-(BUSINESS WIRE)- Pfizer (NYSE: PFE), and Astellas (TSE: 4503) entered into a global standard of care (XTANDI) for adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration resistant prostate cancer. CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with TALZENNA and XTANDI combination has been reported in patients who Buying Ibuprofen in Jamaica experience any symptoms of hypersensitivity to temporarily discontinue XTANDI and promptly seek medical care. Permanently discontinue XTANDI and for one or more of these drugs.

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The primary endpoint of the trial was rPFS, and overall survival (OS) was a key secondary endpoint.

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