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Advise male patients with metastatic castration-resistant prostate cancer (mCRPC)NEW YORK-(BUSINESS WIRE)- Pfizer (NYSE: PFE) announced today that the U. TALZENNA in combination with enzalutamide has not been established in females. A trend in OS favoring TALZENNA plus XTANDI in patients receiving XTANDI. Based on animal studies, TALZENNA may impair fertility in males of reproductive potential.

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